Anti-GJC1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets GJC1 (Gap Junction Protein Gamma 1), the gene that encodes connexin 45, a ~45 kDa transmembrane gap junction protein expressed in cardiac conduction tissue, vascular smooth muscle, and certain neuronal populations. The reagent is supplied as 100 µl of unconjugated IgG in a vial and is intended for Western Blot and immunohistochemistry applications on human, mouse, and rat samples. Researchers use it to study gap junction-mediated cell-cell coupling, cardiac impulse propagation, and the remodeling of connexin expression that occurs in arrhythmogenic heart disease and in developing neural circuits. The polyclonal format offers recognition of multiple epitopes on the connexin 45 C-terminal region, which is useful for detecting endogenous protein in tissue sections and cell lysates. Recommended storage is at -20 °C in working aliquots to limit freeze-thaw cycles, and the reagent is intended for research use only.