Anti-GJB6 Antibody

GJB6 encodes Connexin 30 (Cx30), a transmembrane gap junction protein expressed in the inner ear, epidermis, and central nervous system. Variants in this gene are linked to autosomal recessive non-syndromic hearing loss at the DFNB1 locus and to Clouston syndrome (hidrotic ectodermal dysplasia), making reliable detection tools valuable for auditory and dermatological research.

This unconjugated rabbit polyclonal IgG preparation is supplied by Antibodies.com in a 50 µl volume and has been validated for Western blot (WB) and immunohistochemistry (IHC) applications on human and mouse samples. The reagent provides a flexible option for labs studying connexin trafficking, gap junction assembly, and tissue-specific expression patterns in epithelial and neural contexts.

Researchers working on cochlear gap junction coupling, epidermal barrier function, or neuronal communication networks can use this antibody to probe Cx30 distribution across model systems, supporting both basic discovery and translational studies of connexin-related disease mechanisms.