Anti-GJB3 Antibody

Connexin 31, encoded by the GJB3 gene, is a transmembrane gap junction protein critical for intercellular communication in cochlear, epidermal, and neural tissues. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against GJB3 and validated for Western blot and immunohistochemistry workflows on human and mouse samples. Each vial delivers 100 µl of antibody suitable for detection of endogenous Connexin 31 expression in research models of hearing loss, erythrokeratodermia variabilis, and peripheral neuropathy. The polyclonal format provides recognition of multiple epitopes across the connexin, supporting robust signal in both denaturing gel and fixed-section applications. Supplied as a liquid formulation with no fluorophore or enzyme conjugation, the antibody allows flexible pairing with secondary detection systems tailored to specific experimental designs, including HRP, biotin, or fluorescent labels selected by the end user.