Anti-GJA1 Antibody

The GJA1 gene encodes Connexin 43 (Cx43), the most widely expressed gap junction protein in vertebrate tissues. This rabbit polyclonal antibody from Antibodies.com is raised against GJA1 and validated for Western blot and immunohistochemistry applications. The unconjugated reagent recognizes the target in human, mouse, and rat samples, supporting cross-species studies of cardiac, neural, and epithelial tissue.

For Western blot, the antibody typically highlights the ~43 kDa connexin band in lysates from heart, brain, or transfected cell lines. In IHC applications, it labels gap junction plaques between adjacent cells, a pattern useful for investigating intercellular coupling in development and disease, including cardiac arrhythmia models and oculodentodigital dysplasia research. Each vial contains 100 µl of polyclonal antiserum, and storage at -20°C in working aliquots preserves binding activity through repeated freeze-thaw cycles. The reagent is supplied for research use only in non-clinical laboratory settings.