Anti-GIPC2 Antibody

The antibody recognizes GIPC2, a PDZ domain-containing scaffold protein that has been investigated as a candidate biomarker in oncology research. Published studies have linked altered GIPC2 expression to several malignancies, including breast cancer, where elevated levels have been associated with proliferative and migratory phenotypes in tumor cell populations.

This rabbit polyclonal reagent from Antibodies.com is supplied as 100 µl of unconjugated antiserum, validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples. The polyclonal format provides multi-epitope recognition of the target, supporting consistent detection across denatured lysate preparations as well as fixed tissue sections.

GIPC2 functions as an adaptor that bridges transmembrane receptors with downstream effectors through its single PDZ domain, influencing pathways tied to growth factor signaling and cytoskeletal reorganization. Researchers investigating tumor biology, receptor trafficking, or signal transduction networks can apply this antibody to interrogate endogenous protein levels in cultured cell lines and primary tissue, including archival paraffin-embedded specimens prepared for IHC.