Anti-GHSR Antibody

Developed by Antibodies.com as a polyclonal reagent for investigating ghrelin receptor biology, this unconjugated IgG preparation targets the Growth Hormone Secretagogue Receptor (GHSR), a seven-transmembrane G-protein coupled receptor expressed in the hypothalamus, pituitary, and peripheral metabolic tissues. The antibody is raised in rabbit and recognizes multiple epitopes across the receptor, supporting robust detection in tissue lysates and cell line extracts of human, mouse, and rat origin.

Validated specifically for Western blot workflows, the reagent is supplied as a 50 µl vial of unconjugated IgG, allowing researchers to pair it with HRP-conjugated, fluorophore-labeled, or other secondary detection chemistries of their choosing. Typical downstream uses include probing SDS-PAGE-separated samples transferred to nitrocellulose or PVDF membranes, with expected band patterns around the predicted ~41 kDa receptor mass and higher-molecular-weight species that reflect post-translational modification or receptor heterodimerization. Such experiments support studies of appetite regulation, growth hormone release, and energy homeostasis at the signaling level.

Storage recommendations call for refrigeration and protection from repeated freeze-thaw cycles to preserve activity across multiple experiments; aliquoting upon receipt is advised. The reagent is intended for research use only and is not validated for diagnostic or therapeutic applications.