Anti-GHRH Antibody

Raised in rabbit hosts and supplied as a polyclonal preparation, this unconjugated anti-GHRH reagent from Antibodies.com targets Growth Hormone-Releasing Hormone, the 44-amino acid hypothalamic peptide that drives somatotroph activity in the anterior pituitary. Validated for western blot and immunohistochemistry workflows, the antibody recognizes pro-GHRH and mature peptide forms across human, mouse, and rat samples. Each vial ships as a 100 µl aliquot at 1 mg/ml in PBS buffer supplemented with 0.1% sodium azide and 50% glycerol, allowing direct dilution into standard assay buffers. Investigators studying hypothalamic-pituitary axis signaling, acromegaly models, or somatotroph regulation commonly apply this reagent in chromogenic and fluorescent detection protocols.

The polyclonal format presents multiple epitopes on the GHRH precursor, supporting signal in hypothalamic tissue sections where processing intermediates may be present. Researchers typically aliquot on receipt, store frozen, and protect from light to preserve activity across freeze-thaw cycles; gloves are recommended because sodium azide interferes with horseradish peroxidase-based detection chemistries and is toxic.

Intended for research use only, this GHRH antibody supports endocrinology, neuroscience, and developmental biology laboratories profiling hypothalamic peptide expression and GH-axis regulation.