Anti-Ghrelin Antibody

The 28-amino acid appetite-regulating peptide hormone ghrelin is the target of this rabbit polyclonal reagent, raised for sensitive detection across metabolic, neuroendocrine, and gastrointestinal research workflows. Validated for Western blot and immunohistochemistry on human, mouse, and rat tissue, this unconjugated primary antibody allows flexible pairing with custom secondary detection chemistries such as HRP, biotin, or fluorophore conjugates selected by the end user. Supplied as 100 µl of a 1 mg/ml stock in PBS containing 0.1% sodium azide and 50% glycerol for freeze-thaw stability, the preparation tolerates short-term room temperature shipping and is intended for long-term storage at -20 °C in working aliquots to limit repeated freeze-thaw cycles. Investigators studying obesity, Prader-Willi syndrome, gastric mucosal physiology, cancer-associated cachexia, type 2 diabetes, or the balance between acyl-ghrelin and desacyl-ghrelin rely on this Antibodies.com reagent to localize the hormone in stomach oxyntic glands, pancreatic islets, and hypothalamic arcuate nucleus where it is most abundantly expressed. Polyclonal recognition of multiple epitopes on the mature ghrelin preproprotein improves tolerance for partial degradation during formalin fixation and paraffin embedding, supporting consistent chromogenic signal in archived tissue sections as well as clean bands on denaturing Western blots of cell and tissue lysates.