Anti-GGT1 Antibody

This polyclonal antibody from Antibodies.com targets human GGT1, the membrane-bound gamma-glutamyltransferase 1 enzyme that catalyzes gamma-glutamyl group transfer during glutathione metabolism. The unconjugated reagent is supplied as 100 µl of rabbit antiserum, validated for Western blot and ELISA workflows in human sample analysis. GGT1 expression is widely studied in hepatology and toxicology research, where altered enzymatic activity is associated with cholestasis, alcoholic liver injury, and oxidative stress models. The antibody binds the native human protein expressed on epithelial surfaces of the liver, kidney, and biliary tract, making it useful for characterizing tissue-specific expression and signaling pathways related to redox homeostasis. The unconjugated format allows secondary antibody pairing for immunoblot detection or signal amplification in ELISA assays aimed at quantifying GGT1 levels in cell lysates and tissue extracts. Researchers studying glutathione recycling, xenobiotic detoxification, and hepatic biomarker discovery rely on this reagent to probe GGT1 protein abundance across normal and diseased human tissue panels.