Anti-GGT1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets GGT1 (gamma-glutamyltransferase 1), a membrane-bound enzyme that initiates extracellular glutathione catabolism and is widely studied in hepatic, renal, and bile-acid biology. Raised in rabbit and supplied unconjugated in a 100 µl volume, the reagent is validated for Western blot and immunohistochemistry on human samples, supporting detection of endogenous GGT1 expression in liver tissue sections and lysates.

Gamma-glutamyltransferase 1 is a clinically relevant marker; circulating GGT activity is routinely used to assess hepatobiliary injury, cholestasis, and alcohol-related liver stress, making reliable immunological tools important for translational research into these conditions. As a primary antibody, it can be paired with secondary detection reagents such as HRP- or fluorophore-conjugated anti-rabbit IgG in chromogenic or fluorescence workflows.

Researchers investigating oxidative stress, glutathione homeostasis, drug-induced hepatotoxicity, or tumor-associated GGT expression in epithelial cancers will find this reagent useful for mapping protein localization and abundance across experimental models. Brief centrifugation before use and aliquoting help preserve reagent integrity across multiple experiments.