Anti-GFM2 Antibody

Rabbit polyclonal antibody targeting GFM2, the mitochondrial elongation factor G2 (also called EFG2 or mEF-G 2). This GTP-binding protein drives translocation of peptidyl-tRNA from the A-site to the P-site of the mitochondrial ribosome during organellar protein synthesis, and pathogenic variants in the gene cause combined oxidative phosphorylation deficiency type 39. Antibodies.com supplies this unconjugated reagent as 100 µl of polyclonal rabbit antibody validated for western blot and immunofluorescence on human and mouse samples. Investigators studying mitochondrial translation, respiratory chain assembly, and inherited OXPHOS disorders use it to monitor GFM2 steady-state levels, assess mitochondrial ribosome integrity, and probe the biogenesis of electron transport chain subunits in cell and tissue models.