Anti-GEMIN2 Antibody

Raised in rabbit against the GEMIN2 target, this polyclonal antibody from Antibodies.com enables detection of Gem Nuclear Organelle Associated Protein 2 by western blot. GEMIN2, also known as SIP1, functions as a core component of the survival motor neuron (SMN) complex and supports the cytoplasmic assembly of small nuclear ribonucleoproteins required for pre-mRNA splicing. Mutations affecting SMN complex assembly are implicated in spinal muscular atrophy, making GEMIN2 a target of interest in motor neuron disease research and spliceosome biology studies. Supplied as 100 µl of unconjugated IgG in a vial, the reagent is validated for human and mouse reactivity and supports western blot analysis of endogenous protein levels in cultured cell lysates and tissue homogenates. The polyclonal format recognizes multiple epitopes on the GEMIN2 protein, providing robust detection across a range of experimental conditions, and the unconjugated presentation allows flexible pairing with secondary antibodies of the researcher's choice for chromogenic or fluorescent readout.