Anti-GDI1 Antibody

This polyclonal antibody from Antibodies.com targets GDI1 (GDP Dissociation Inhibitor 1), a cytoplasmic regulator of Rab GTPase activity that retains Rab proteins in their inactive GDP-bound state and participates in intracellular vesicle trafficking. The reagent is raised in rabbit, supplied as 100 µL of unconjugated antiserum, and has been validated for western blot, immunohistochemistry, and immunofluorescence on human samples. GDI1 expression is relevant to studies of membrane transport, synaptic vesicle recycling, neuronal signaling, and X-linked intellectual disability, where mutations in the GDI1 gene have been associated with conditions such as MRX41 and MRX48. Researchers examining Rab-mediated vesicular transport, neurodevelopmental biology, or GDI1-associated disorders can use this antibody to detect endogenous protein in cell lysates and tissue sections. The unconjugated format supports flexible pairing with custom secondary antibodies and tailored signal amplification in experimental workflows.