Anti-GDF6 Antibody

This unconjugated rabbit polyclonal antibody targets human Growth Differentiation Factor 6 (GDF6), a secreted signaling protein of the TGF-β superfamily that directs skeletal patterning, joint morphogenesis, and aspects of neural and ocular development. The reagent is supplied as 100 µl of polyclonal antiserum raised in rabbit, intended for western blot and immunohistochemistry workflows on human samples. Loss-of-function variants in GDF6 have been linked to Klippel-Feil syndrome, Leber congenital amaurosis, and isolated microphthalmia, so detection of endogenous protein in tissue sections and lysates supports research in developmental biology, ophthalmology, and skeletal dysplasia. Provided by Antibodies.com as a primary antibody without reporter conjugation, it can be paired with secondary detection reagents chosen by the end user. Refrigerate on receipt and avoid repeated freeze-thaw cycles to preserve binding activity across multiple experiments.