Anti-GDF15 Antibody

A rabbit polyclonal reagent from Antibodies.com targets Growth Differentiation Factor 15 (GDF15), a stress-responsive cytokine belonging to the TGF-β superfamily. Also known as MIC-1, NAG-1, PDF, PLAB, and PTGFB, GDF15 participates in inflammatory signaling, apoptosis regulation, cachexia, and metabolic stress pathways, and has drawn attention as a candidate biomarker in oncology and cardiovascular research.

Provided as 200 µl of unconjugated IgG in liquid format, this primary antibody has been validated for Western blot (WB) and immunohistochemistry (IHC) workflows. The reagent cross-reacts with human, mouse, and rat samples, supporting translational studies across species. Investigators studying tumor progression, mitochondrial stress, anorexia-cachexia syndrome, pregnancy-associated signals, or GFRAL-mediated appetite regulation routinely employ this reagent.

Aliquot upon receipt to limit freeze-thaw cycles and protect from light. Applications span Western blot analysis of GDF15 expression in cell lysates and immunohistochemistry on formalin-fixed paraffin-embedded tissue sections. The unconjugated format allows flexibility for downstream detection chemistry selection and custom secondary antibody pairing in both WB and IHC pipelines.