Anti-GCNT1 Antibody

Affinity-purified polyclonal reagent raised in rabbit against the human GCNT1 protein, also known as glucosaminyl (N-acetyl) transferase 1 or C2GnT. This enzyme initiates I-branching on mucin-type O-linked glycans and has been linked to altered cell-surface glycosylation in several epithelial carcinomas. Supplied as 100 µl of unconjugated IgG in a vial, this Primary Antibody from Antibodies.com is intended for Western blot detection of endogenous human GCNT1 in cell and tissue lysates. The polyclonal IgG isotype supports standard chromogenic or chemiluminescent readout with anti-rabbit HRP or alkaline phosphatase secondary reagents. For long-term handling, aliquot and freeze at -20 °C, avoiding repeated freeze-thaw cycles; refrigerated storage at 4 °C is suitable for active use within a few weeks. For research use only, the reagent is applied to in vitro studies of mucin biosynthesis, O-glycan remodeling, and tumor-associated carbohydrate antigen expression, including colorectal cancer cell lines and patient-derived tissue samples.