Anti-GCN5 (G720) Antibody

Histone acetyltransferase GCN5 (also known as KAT2A) functions as a catalytic subunit of the STAGA and PCAF transcriptional coactivator complexes, where it acetylates lysine residues on histones H3 and H4 to regulate chromatin accessibility and gene expression. This rabbit polyclonal antibody, raised against a synthetic peptide centered on the G720 residue, recognizes the full-length GCN5 protein in human, mouse, and rat samples.

Validated for Western blot (WB) and immunohistochemistry (IHC), the unconjugated antibody is supplied by Antibodies.com as 100 µl of a 1 mg/ml stock in phosphate-buffered saline (PBS, pH 7.2) with 0.05% sodium azide as a preservative. Applications include profiling GCN5 expression and subcellular distribution across tissue sections and cell lysates in studies of epigenetic regulation, transcription factor recruitment, and nuclear signaling pathways.

Polyclonal reactivity broadens epitope coverage for detection of native and post-translationally modified forms of the enzyme, supporting chromatin biology investigations and disease models where GCN5 dysregulation contributes to altered transcription programs.