Anti-GBE1 Antibody

GBE1 encodes 1,4-alpha-glucan branching enzyme, the protein responsible for introducing alpha-1,6-glycosidic branch points into glycogen during polymer biosynthesis. This polyclonal reagent from Antibodies.com is raised in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a 100 µl aliquot. The unconjugated antibody is validated for Western blot and immunohistochemistry on human, mouse, and rat samples, supporting studies of glycogen metabolism and the cellular distribution of the branching enzyme.

Loss-of-function changes in GBE1 are implicated in glycogen storage disease type IV (Andersen disease) and adult polyglucosan body disease, so this reagent is commonly cited in research characterising glycogen accumulation in liver, muscle, and neural tissue. Researchers use it to probe branching enzyme expression in cell culture lysates and formalin-fixed tissue sections, with the polyclonal format providing recognition of multiple epitopes across the target protein.

Storage: aliquot and store at -20 °C; avoid repeated freeze-thaw cycles. The 50% glycerol cryoprotectant keeps the solution liquid at standard freezer temperatures. For research use only.