Anti-GATA6 Antibody

This rabbit polyclonal reagent from Antibodies.com targets the GATA6 zinc-finger transcription factor in human samples and is supplied as 100 µl of unconjugated IgG for Western blot workflows. GATA6 regulates gene expression programs in endoderm-derived tissues including the pancreas, liver, lung, and gut epithelium, where it directs organogenesis and lineage specification during embryonic development. Researchers deploy the antibody to probe GATA6 protein levels in studies of pancreatic β-cell differentiation, cardiac morphogenesis, and the pathogenesis of gastric, pancreatic, and colorectal carcinomas, where altered GATA6 expression is associated with tumor progression. The antibody is affinity-purified against recombinant GATA6 and validated for use on whole-cell lysates and tissue extracts separated by SDS-PAGE. For best results, store at -20°C in working aliquots to limit freeze-thaw cycles and protect from light when not in use.