Anti-GATA4 Antibody [Assigned #A3600]

This mouse monoclonal IgG antibody from Antibodies.com targets the GATA4 zinc-finger transcription factor and is supplied as 50 µl of unconjugated reagent in a single-use vial. Validated for Western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation, the antibody detects endogenous GATA4 in human, mouse, and rat samples. GATA4 is a sequence-specific DNA-binding protein that governs cardiac, gonadal, and endodermal gene expression programs, making this reagent a useful tool for studies of heart development, sex determination pathways, and hepatic lineage commitment. For routine handling, aliquot the stock upon arrival and store frozen at low temperature, limiting freeze-thaw cycles to preserve binding activity. Researchers apply this reagent in cell culture and tissue sections to characterize cardiomyocyte differentiation, map GATA4 occupancy at native target promoters, and probe tissue-specific transcription during embryonic organogenesis.