Anti-GATA2 Antibody

This rabbit polyclonal antibody targets GATA2, a zinc-finger transcription factor essential for hematopoietic stem cell maintenance and early vascular development. Manufactured by Antibodies.com, the reagent is supplied as a 100 µl vial at 1 mg/ml in PBS containing 0.1% sodium azide, with 50% glycerol added as a cryoprotectant to minimize damage during frozen storage.

The unconjugated antibody is validated for Western blot and immunohistochemistry across human, mouse, and rat samples, supporting investigations of transcriptional control in early myeloid and lymphoid lineages. Researchers commonly apply this reagent when studying GATA2 haploinsufficiency disorders, including MonoMAC syndrome and Emberger syndrome, as well as acute myeloid leukemia where deregulated GATA2 activity contributes to disease progression. The polyclonal format offers recognition of multiple epitopes on the full-length GATA2 protein, which can improve signal robustness in studies of chromatin-bound or post-translationally modified forms of the factor.