Anti-GATA-1 (phospho-S142) Antibody

Phosphorylation at serine 142 modulates GATA-1 transcriptional activity in erythroid and megakaryocytic lineages, and this rabbit polyclonal antibody from Antibodies.com is raised specifically against that phosphorylated epitope to support signaling research in hematopoietic systems. Supplied as 100 µl of unconjugated reagent at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, the polyclonal format offers broader epitope coverage around the phospho-S142 site, which is known to influence DNA binding and cofactor recruitment. Validated for western blot, immunohistochemistry, and immunoprecipitation on human, mouse, and rat samples, the reagent enables chromatin studies, lineage tracing, and pathway analysis where phosphorylation status of GATA-1 is the experimental readout. For storage, aliquot upon receipt and store at -20 °C, avoiding repeated freeze-thaw cycles to preserve phospho-specific reactivity; the formulation includes sodium azide as a preservative.