Anti-GATA-1 Antibody

This polyclonal reagent from Antibodies.com is a rabbit-derived primary antibody raised against GATA-1, a zinc-finger transcription factor best known for directing erythroid and megakaryocytic gene programs. The unconjugated antibody is supplied in a 100 µl vial and is validated across western blot (WB), immunohistochemistry (IHC), immunoprecipitation (IP), immunofluorescence (IF), and ELISA workflows. Reactivity is confirmed for human, mouse, and rat, supporting translational studies that span cell-line work, primary hematopoietic cultures, and rodent disease models.

GATA-1 governs expression of erythroid markers such as globin loci, and the antibody is commonly used to confirm differentiation status in erythroleukemia cell lines, to track chromatin-associated factor occupancy by immunoprecipitation, and to localize the protein in tissue sections from developing fetal liver or adult bone marrow. Aliquot upon first use to limit freeze-thaw cycles, store refrigerated for short-term handling, and keep frozen in working aliquots for longer projects. Intended for research use only, this Antibodies.com reagent is suited to laboratory investigation of hematopoietic transcription and related signaling questions.