Anti-Gasdermin C Antibody

Raised in rabbit, this polyclonal antibody recognizes Gasdermin C (GSDMC), a pore-forming member of the gasdermin family that has been linked to pyroptotic cell death and to dysregulated expression in several solid tumors. The unconjugated reagent is supplied as 100 µl of antiserum and is validated for Western blot and ELISA workflows against human samples, supporting studies of intestinal epithelium, breast cancer cell lines, and other GSDMC-expressing systems where researchers need to track full-length protein versus cleaved fragments. Because polyclonal reagents recognize multiple epitopes across the target, they are often used to map processing events that accompany gasdermin activation, an area of active investigation in inflammatory and oncologic research. The reagent performs in standard SDS-PAGE transfer conditions and in antigen-coated ELISA plate formats, giving laboratories working on pyroptosis, mucosal biology, or tumor signaling a flexible tool to probe GSDMC abundance and cleavage state. Antibodies.com provides this reagent for scientists investigating the gasdermin family's contribution to programmed cell death pathways and epithelial homeostasis.