Anti-GAP43 (phospho-S41) Antibody

Phospho-specific rabbit polyclonal reagent from Antibodies.com raised against GAP43 phosphorylated at serine 41, a major protein kinase C substrate in developing and regenerating neurons. This primary antibody is supplied as 100 µl of a 1 mg/ml stock in phosphate buffered saline (pH 7.2) with 0.05% sodium azide and is unconjugated for flexible detection chemistry.

Validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples, the reagent supports studies of axonal outgrowth, growth cone dynamics, nerve regeneration, and LTP-associated synaptic remodeling in hippocampal and peripheral nervous tissue. Researchers investigating brain ischemia, traumatic neural injury, neurodegenerative disease models, and activity-dependent plasticity routinely use it to monitor site-specific PKC-mediated phosphorylation in fixed sections and detergent lysates.