Anti-GAP43 (Ab-41) Antibody

Produced by Antibodies.com, this affinity-purified reagent is a rabbit polyclonal preparation raised against a synthetic peptide spanning residues38–43 (Q-A-S-F-R) of human GAP43, also known as growth-associated protein 43, neuromodulin, axonal membrane protein GAP-43, neural phosphoprotein B-50, or pp46. The unconjugated antibody is supplied as a 50 µl aliquot at 1.0 mg/mL in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, and it is shipped on cold packs at 4 °C; for longer-term storage it should be aliquoted and held at –20 °C while avoiding repeated freeze/thaw cycles. The antibody recognizes the endogenous total GAP43 protein and has been validated for Western blotting, immunohistochemistry on paraffin sections, and immunocytochemistry/immunofluorescence, making it well suited to studies of neuronal development, axonal regeneration, and plasticity-related signaling in neural tissue. Reactivity has been confirmed against human, mouse, and rat samples, broadening its utility across common mammalian model systems and human clinical specimens. Quality-control images on the Antibodies.com product page include representative immunohistochemical staining of paraffin-embedded human breast carcinoma tissue, alongside a peptide-blocking control that confirms epitope specificity. As supplied, the polyclonal IgG fraction was generated by immunizing rabbits with a KLH-conjugated synthetic peptide and purified by affinity chromatography on an epitope-specific peptide column, ensuring minimal cross-reactivity and consistent lot-to-lot performance for research use only.