Anti-GAP-43 Antibody

GAP-43 (Growth Associated Protein 43) is a nervous system-specific phosphoprotein concentrated in neuronal growth cones and presynaptic terminals, where it regulates axon extension, pathfinding, and synaptic remodeling during development and after neural injury. Antibodies.com offers a rabbit polyclonal, unconjugated antibody raised against this target, suitable for Western blot, immunohistochemistry, and ELISA workflows across human, mouse, and rat samples.

The polyclonal format recognizes multiple epitopes on GAP-43, which can improve signal in IHC on fixed brain sections and in WB of neural-tissue lysates. Each 100 µl vial supports multiple membranes or slide sets, and aliquoting on first use is recommended to limit freeze-thaw cycles. Refrigerate upon receipt; for long-term storage, keep frozen and protect from light to preserve reagent activity.

Common research applications include mapping regenerating axons after spinal-cord or peripheral-nerve injury, tracking neurite outgrowth in cell-culture models of neuronal differentiation, and quantifying GAP-43 levels as a readout of synaptic plasticity. For research use only.