Anti-GALNT3 Antibody

The Anti-GALNT3 polyclonal antibody from Antibodies.com is a rabbit IgG reagent raised against polypeptide N-acetylgalactosaminyltransferase 3, the Golgi-resident glycosyltransferase that initiates mucin-type O-glycosylation by transferring N-acetylgalactosamine to serine and threonine residues. Supplied as an unconjugated antiserum in a 50 µl vial, this reagent is validated for Western blot detection of the human target in cell lysates and tissue homogenates.

GALNT3 expression is most prominent in the pancreas, kidney, and several endocrine tissues, and the protein has been linked to disorders of phosphate metabolism, including familial tumoral calcinosis, where loss-of-function variants drive hyperphosphatemia and ectopic calcification. Researchers studying O-glycosylation pathways, phosphate homeostasis, or glycosyltransferase biology can use this reagent to probe endogenous GALNT3 levels under reducing conditions.

For best results, aliquot the antibody upon arrival and store at -20 °C in working volumes to limit freeze-thaw cycles; short-term storage at 4 °C is appropriate for active use. The IgG isotype supports standard chemiluminescent and colorimetric Western blot workflows with anti-rabbit secondary reagents, and the unconjugated format leaves labeling chemistry open for downstream applications.