Anti-GALNT2 Antibody

Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) is a Golgi-resident enzyme that catalyzes the transfer of N-acetylgalactosamine to serine and threonine residues, initiating mucin-type O-linked glycosylation of substrate proteins. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against GALNT2 and was selected for cross-reactivity with Human, Mouse, and Rat samples, making it broadly applicable across species in cardiovascular, metabolic, and cell biology research.

The antibody is supplied as 100 µl at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, providing a stable, ready-to-use stock. It should be stored at -20°C in small aliquots to limit freeze-thaw cycles and protect immunoglobulin activity. Validated application areas include western blot for detecting endogenous GALNT2 expression across cultured cell lines and tissue lysates, immunofluorescence for subcellular localization within the Golgi compartment, and immunohistochemistry on fixed paraffin or frozen sections.

Investigators studying HDL-cholesterol regulation, hepatic lipid handling, mucin biosynthesis, and O-glycosylation pathways commonly rely on this target. The polyclonal format provides recognition of multiple epitopes, which supports robust signal in heterologous expression systems as well as in primary tissue samples where post-translational modification patterns may vary.