Anti-GAL Antibody

Galanin (GAL) is a 29-30 amino acid neuropeptide expressed throughout the central and peripheral nervous systems, where it modulates nociception, feeding behavior, memory, and neurotransmitter release through three G protein-coupled receptors (GalR1, GalR2, GalR3). This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against galanin and applied in immunohistochemistry (IHC) on rat tissue. Provided as an IgG preparation in a 50 µl volume, the reagent supports direct detection of endogenous galanin in fixed sections without secondary-labeling interference. Researchers mapping neuropeptide distribution in hypothalamic feeding circuits, dorsal root ganglion sensory neurons, and pancreatic islet biology rely on anti-GAL antibodies to characterize peptide localization and co-expression with classical neurotransmitters. The polyclonal nature of the reagent increases recognition of multiple epitopes on the galanin precursor and its processed fragments, supporting consistent staining across rat brain regions including the arcuate nucleus, locus coeruleus, and spinal cord dorsal horn.