Anti-GAGE7 Antibody

The GAGE7 target is a member of the cancer-testis antigen family, proteins that remain largely silent in adult somatic tissues but become aberrantly expressed across a broad range of human malignancies. This unconjugated polyclonal reagent from Antibodies.com supports detection of human GAGE7 in Western blot and immunohistochemistry workflows, two of the most widely used readouts in tumor biology research. Supplied as 100 µl of polyclonal antiserum raised in rabbit, the antibody is intended for profiling cell lines and tissue specimens where GAGE7 reactivation has been reported, including melanoma as well as several carcinomas of the lung, breast, and head and neck. Because GAGE7 expression in normal tissue is essentially confined to the testis, positive staining in other contexts is interpreted as tumor-associated antigen reactivation, which makes this reagent a useful tool for cancer immunology, tumor marker studies, and antigen discovery pipelines aimed at identifying targets for immunotherapy.