Anti-GAD2 Antibody

For research use only. This rabbit polyclonal antibody targets GAD2 (glutamic acid decarboxylase 2), the 65 kDa enzyme isoform that synthesizes the inhibitory neurotransmitter GABA from L-glutamate in central nervous system neurons and pancreatic islet beta cells. Available from Antibodies.com as 100 µL of unconjugated antisera, the reagent is validated for Western blot and immunohistochemistry workflows across Human, Mouse, and Rat tissue or cell samples.

The polyclonal antibody format allows recognition of multiple epitopes on the GAD2 target, which is useful for studies of GABAergic signaling, pancreatic islet biology, and autoantibody screening in type 1 diabetes research. Each vial of unconjugated antibody can be paired with an HRP- or fluorophore-conjugated secondary appropriate to the chosen detection system. For best results, prepare small aliquots before first use to minimize freeze-thaw cycles, and store refrigerated between experiments according to the lot-specific data sheet shipped with the product.