Anti-GABRA3 Antibody

Raised in rabbit against the gamma-aminobutyric acid type A receptor alpha 3 subunit, this unconjugated IgG polyclonal antibody from Antibodies.com detects GABRA3, a ligand-gated chloride channel component that mediates fast inhibitory synaptic transmission in the central nervous system. Validated for Western blot applications, the reagent recognizes the target in human, mouse, and rat samples, supporting research into GABAergic signaling, receptor subunit composition, and neurological mechanisms.

Supplied as 50 µl of liquid, the antibody is suited for researchers studying epilepsy-associated receptor variants, neurodevelopmental disorders, and modulation of inhibitory neurotransmission. The polyclonal format offers broader epitope coverage for tracking endogenous GABRA3 expression across cell and tissue lysates. Researchers are advised to aliquot the antibody upon receipt and avoid repeated freeze-thaw cycles to preserve reactivity across multiple experiments.

For research use only, this primary antibody enables investigation of alpha 3 subunit contribution to GABA-A receptor pharmacology, including studies of benzodiazepine binding sites, tonic inhibition, and subunit-specific trafficking in neuronal and heterologous expression systems.