Anti-GABRA3 Antibody

Affinity-purified polyclonal reagent raised in rabbit recognises the alpha-3 subunit of the human type A GABA receptor, an IgG-class antibody from Antibodies.com validated for western blot detection across human, mouse, and rat samples. Supplied as a 200 µl liquid vial in unconjugated format, the reagent pairs cleanly with HRP- or fluorophore-labelled secondary antibodies and lets researchers customise detection chemistry for downstream western blot workflows.

The GABRA3 subunit assembles into ligand-gated chloride channels responsible for fast inhibitory signalling in the central nervous system, with documented expression in the cerebral cortex, hippocampus, and thalamus. Researchers studying epilepsy, Angelman syndrome, and related neurodevelopmental or affective disorders commonly probe subunit levels and distribution in neuronal tissue to follow changes driven by pharmacological, genetic, or behavioural interventions in rodent models and human-derived material.

Brief handling guidance: store the vial refrigerated at 4°C for active use, aliquot and freeze at -20°C for longer-term storage, and minimise freeze-thaw cycles to preserve binding activity. Because the reagent is unconjugated, this Antibodies.com antibody is also compatible with custom labelling strategies beyond the standard western blot workflow.