Anti-GABPB2 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets human GABPB2 (GA-binding protein subunit beta-2), a transcription factor subunit that heterotetramerizes with GABPA to regulate nuclear-encoded mitochondrial genes and ribosomal protein expression. Supplied as 100 µl of liquid, the reagent is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human samples, supporting both immunoblotting of cell or tissue lysates and chromogenic localization in fixed tissue sections. The polyclonal format recognizes multiple epitopes across the target, an advantage when probing endogenous GABPB2 levels under varying expression conditions. Researchers investigating mitochondrial biogenesis, oxidative phosphorylation control, or the broader GABP transcriptional network can deploy this reagent to assess target abundance, isoform patterns, and tissue distribution. For handling, working aliquots are kept refrigerated at 4°C, with longer-term storage at -20°C to preserve antibody activity across repeated freeze-thaw cycles. The unconjugated format leaves the choice of reporter open, allowing downstream conjugation to HRP, biotin, or fluorophores depending on the chosen detection chemistry.