Anti-GABBR2 Antibody

This polyclonal rabbit IgG antibody from Antibodies.com targets GABBR2 (Gamma-Aminobutyric Acid Type B Receptor Subunit 2), a metabotropic G-protein-coupled receptor that mediates slow, prolonged inhibitory neurotransmission throughout the central nervous system. Supplied as 50 µl of unconjugated reagent and validated for Western blot detection in human, mouse, and rat samples, it enables researchers to probe receptor expression in neuronal lysates and tissue homogenates. The reagent supports studies of GABAergic signaling, synaptic plasticity, and neurological disease mechanisms including epilepsy and substance-use disorders. Because GABBR2 obligately heterodimerizes with GABBR1 at the cell surface to form a functional GABA_B receptor, this antibody is useful for characterizing subunit expression in transfected cell lines as well as endogenous brain tissue. The polyclonal format ensures recognition of multiple epitopes on the target, improving detection robustness across varied experimental conditions and sample preparations.