Anti-GABBR1 Antibody

This unconjugated rabbit polyclonal IgG antibody from Antibodies.com targets GABBR1, the gamma-aminobutyric acid type B receptor subunit 1, a metabotropic G protein-coupled receptor central to inhibitory neurotransmission in the mammalian central nervous system. Raised in rabbit host animals and purified as a polyclonal reagent, it is validated for Western blot detection of the human receptor, supporting studies of GABAergic signaling, neuronal excitability, and subunit expression in brain tissue lysates. The 200 µl liquid format provides ample volume for multiple gel-loading replicates, and the unconjugated format lets researchers pair the reagent with their preferred HRP- or fluorophore-conjugated secondary antibodies. For storage, refrigerate the aliquoted antibody and limit freeze-thaw cycles to preserve binding activity across repeated blots. Because GABBR1 assembles into obligate heterodimers with GABBR2 and is implicated in research areas spanning epilepsy, neuropathic pain, anxiety, addiction, and schizophrenia, reliable detection of the subunit remains a routine need in neuroscience and neuropharmacology laboratories working with human cell lines and primary tissue samples.