Anti-GABBR1 Antibody

Produced in rabbit as a polyclonal IgG reagent against the human GABA type B receptor subunit 1, this unconjugated primary antibody from Antibodies.com is supplied at 100 µl and validated for Western blot applications. GABBR1 encodes a metabotropic G protein-coupled receptor that mediates the slow, inhibitory component of GABAergic neurotransmission in the central nervous system, where it assembles as an obligate heterodimer with GABBR2 to form the functional GABA-B receptor. Researchers apply the antibody to neuronal and brain-tissue lysates to probe receptor expression and regulation; on denaturing SDS-PAGE the target resolves at an apparent molecular weight consistent with the predicted ~108 kDa subunit mass. For working use, the antibody should be stored at -20 °C in single-use aliquots to minimize repeated freeze-thaw cycles and preserve reagent performance. The unconjugated IgG format pairs cleanly with standard anti-rabbit HRP or fluorescent secondaries, supporting chemiluminescent or fluorescent immunoblot detection of GABBR1 in human samples.