Anti-GABARAP Antibody

This rabbit polyclonal antibody from Antibodies.com targets GABARAP, a small ubiquitin-like protein of the ATG8/LC3 family that functions as a key autophagy receptor. GABARAP participates in autophagosome biogenesis and maturation, mediates tethering between autophagosomes and binding partners through LIR (LC3-interacting region) docking motifs, and contributes to intracellular trafficking of GABA_A receptors along with other membrane cargo. The unconjugated reagent is supplied as 100 µl and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat specimens, supporting neuroscience research, autophagy pathway studies, and investigations of receptor-trafficking mechanisms in tissues such as brain, spinal cord, and muscle as well as in cultured mammalian cell lines.