Anti-GABAB R1 (P931) Antibody

Raised in rabbit, this unconjugated polyclonal antibody from Antibodies.com targets the GABAB R1 subunit, a G-protein coupled receptor broadly expressed in central nervous system tissue and central to slow inhibitory synaptic transmission. The reagent is supplied at 1 mg/ml in a 100 µl vial of Phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, and is validated for Western blot and immunofluorescence workflows on human, mouse, and rat samples. Each vial is shipped refrigerated; aliquot on receipt and store frozen to limit freeze-thaw cycles and preserve binding activity. Provided unconjugated, the antibody gives investigators flexibility to pair it with their own secondary reporter, fluorescent probe, or HRP conjugate, fitting standard immunoblotting of membrane fractions and immunostaining of brain sections. Researchers studying G-protein coupled receptor signaling, GABAergic synapse biology, or the regulation of inhibitory receptors routinely use it on denaturing gels and fixed cell preparations to detect the native receptor in relevant tissue.