Anti-GA45G Antibody

The GADD45G protein (also referenced as GA45G or CR6) belongs to the growth arrest and DNA damage-inducible gene family, acting downstream of p53 to coordinate cell cycle arrest, DNA repair, and apoptotic signaling under genotoxic stress. This polyclonal reagent from Antibodies.com is raised in rabbit and supplied as 100 µl of unconjugated antiserum, providing flexibility to pair with user-selected secondary detection chemistries including HRP, biotin, or fluorophore conjugates.

Validated for Western blot, immunohistochemistry, and immunofluorescence on human samples, the antibody supports investigation of DNA damage responses, stress kinase signaling, and tumor suppression pathways in which GADD45G expression is commonly dysregulated. Polyclonal recognition of multiple epitopes aids detection across denatured lysates used in WB and formalin-fixed tissue sections used in IHC, and enables visualization of subcellular distribution by IF microscopy. Researchers apply this reagent to characterize stress-induced expression changes, profile tissue-specific localization in tumor and normal specimens, and explore the contribution of GADD45G to differentiation, senescence, and immune regulation.

The unconjugated format allows adaptation to chromogenic, chemiluminescent, or fluorescence-based readouts, and the 100 µl volume supports multiple experimental replicates across independent sample sets.