Anti-G2A Antibody

Supplied as a 100 µl aliquot of unconjugated polyclonal antiserum from Antibodies.com, this G2A-targeting reagent was raised in rabbits and recognizes the G protein-coupled receptor GPR132. Validated applications include western blot, immunofluorescence, and ELISA, with reactivity confirmed against human, mouse, and monkey samples. Polyclonal preparations capture multiple epitopes across the G2A target, a stress-responsive receptor originally linked to cell cycle arrest in fibroblasts and to oncogenic signaling in prostate cancer research. Lysophosphatidylcholine and certain oxidized lipid species have been reported to act through G2A, placing the receptor at the intersection of inflammation studies, immune cell migration assays, and tumor microenvironment investigations. Researchers working on apoptosis regulation, atherosclerosis models, and innate immune signaling use this reagent to probe receptor localization and downstream activation. The unconjugated format gives laboratories flexibility to pair the antibody with custom secondary antibodies and detection chemistries. For storage, the vial should be aliquoted to limit freeze-thaw cycles, handled at refrigerated temperatures for active use, and protected from light during long-term storage.