Anti-G-CSFR Antibody [S-1252]

Targeting the human Granulocyte Colony Stimulating Factor Receptor, also annotated as CSF3R and CD114, the recombinant mouse monoclonal antibody clone S-1252 from Antibodies.com is supplied as a lyophilised 100µg preparation in unconjugated IgG1 format. Validated for Western blot detection of endogenous receptor in human cell lysates, the reagent supports research into neutrophil biology, granulopoiesis, and acute myeloid leukemia where altered G-CSFR signaling has been investigated.

Produced in murine hosts under monoclonal conditions, the antibody delivers lot-to-lot reproducibility for studies of myeloid differentiation and receptor expression. Researchers routinely apply it to whole-cell extracts from human myeloid lines such as HL-60 and U937 to follow receptor levels during induced differentiation. The unconjugated format pairs cleanly with chosen secondary antibodies, including HRP, fluorophore, or biotin conjugates, while the lyophilised presentation simplifies handling; reconstitution followed by aliquoting is recommended to limit repeated freeze-thaw cycles of the working solution.