Anti-G-CSFR Antibody

The G-CSFR (Granulocyte Colony-Stimulating Factor Receptor) is a cell-surface receptor that governs neutrophil production, myeloid lineage commitment, and bone marrow progenitor proliferation downstream of G-CSF signaling. This unconjugated rabbit polyclonal reagent from Antibodies.com targets the human receptor and is validated for western blot and ELISA workflows, supporting studies in hematopoiesis, granulopoiesis, and immune cell differentiation.

Investigators working on acute myeloid leukemia, severe congenital neutropenia, or G-CSF signaling cascades can use the antibody to probe receptor expression in cell lysates and to quantify soluble or cell-associated receptor levels in immunoassays. Because the reagent is polyclonal, it recognizes multiple epitopes across the receptor, which is useful when tracking expression changes, isoform variation, or truncation mutants linked to disease phenotypes and inherited neutrophil disorders.

The antibody is supplied as a 100 µl liquid aliquot and ships unconjugated, giving flexibility to pair it with custom detection chemistries, HRP- or fluorophore-labeled secondaries, or laboratory-specific ELISA platforms. For routine handling, the reagent should be refrigerated, protected from light, and kept on ice during use; small aliquots minimize freeze-thaw cycles and preserve binding activity over extended experimental campaigns.