Anti-Gα olf Antibody

This rabbit-derived polyclonal reagent from Antibodies.com targets the alpha subunit of the stimulatory G protein associated with olfactory signal transduction (Gα olf, encoded by GNAL). Raised in rabbit and supplied as 100 µl of unconjugated antiserum, it is validated for western blot, immunohistochemistry, and ELISA workflows and shows reactivity with human, mouse, and rat samples. The antibody recognizes the Gα olf polypeptide expressed in olfactory epithelium and in striatal medium spiny neurons, where GNAL contributes to D1-type dopamine receptor signaling through adenylyl cyclase activation. Researchers investigating olfactory transduction, basal ganglia dopamine signaling, or adult-onset dystonia (DYT25, linked to GNAL mutations) use this reagent to localize and quantify the protein in tissue sections and lysates. The unconjugated format supports flexible secondary antibody selection for diverse imaging or immunoblot readouts. For long-term storage, aliquot the vial and freeze; repeated freeze-thaw cycles should be avoided to preserve antibody activity.