Anti-FZR1 Antibody

Raised in rabbits against the Fizzy/Cell Division Cycle 20-Related 1 (FZR1) protein, this polyclonal reagent from Antibodies.com supports studies of cell cycle regulation through the anaphase-promoting complex/cyclosome (APC/C) pathway that governs mitotic exit and chromosome segregation. The antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as 100 µl of unconjugated material in a vial. Applications include Western blot, immunohistochemistry, and immunofluorescence, with reactivity validated against human, mouse, and rat samples. The polyclonal format recognizes multiple epitopes on the WD40-repeat activator, which is helpful when probing post-translational modifications or alternative isoforms of FZR1. Researchers commonly deploy this reagent to investigate APC/C substrate turnover, spindle assembly checkpoint signaling, and the DNA damage response. Aliquot the antibody upon first use to limit freeze-thaw cycles and store refrigerated in the dark, since sodium azide is included as a preservative.