Anti-FYN (phospho Y416) + Lck (phospho Y416) Antibody

Antibodies.com offers this rabbit polyclonal IgG reagent raised against the activated forms of FYN and Lck, two Src-family non-receptor tyrosine kinases phosphorylated at the conserved Y416 activation loop. Phosphorylation at tyrosine 416 marks the catalytically engaged state of these kinases, and the reagent recognizes that activation-specific modification in lysates prepared from Human and Mouse samples.

Provided unconjugated in a 50 µl vial, the antibody is validated for Western Blot (WB) workflows, where it can be paired with secondary antibodies of choice for chemiluminescent or fluorescent detection. Polyclonal reactivity against two related phospho-epitopes from a single host species allows side-by-side comparison of FYN and Lck activation within the same immunoblot, supporting studies of T-cell receptor signaling, lymphocyte activation, neuronal development, and broader Src-family kinase research.

Rabbit IgG isotype, stored at -20 °C in working aliquots to limit freeze-thaw cycles. Research use only.