Anti-FUT4 Antibody

FUT4 (Fucosyltransferase 4) is a Golgi-membrane enzyme that transfers fucose from GDP-fucose onto N-acetylglucosamine residues, producing the Lewis X (LeX, CD15) trisaccharide and related fucosylated epitopes. These structures decorate glycoproteins and glycolipids on leukocytes, epithelial cells, and many tumors, where they act as selectin ligands driving rolling adhesion during leukocyte trafficking and hematogenous metastasis. The rabbit polyclonal IgG preparation from Antibodies.com is supplied as 200 µl of unconjugated antiserum validated for Western blot, immunohistochemistry on formalin-fixed tissue sections, and flow cytometry staining of Human and Mouse cells. Researchers use it to map fucosylation patterns in immune cell subsets, characterize cancer stem cell populations expressing CD15/LeX, and probe FUT4 transcriptional regulation during myeloid differentiation. Storage at -20 °C in single-use aliquots preserves reactivity across multiple freeze-thaw cycles, and the unconjugated format allows users to couple it to HRP, biotin, or fluorophores of choice for custom detection chemistries.