Anti-FTO Antibody

FTO (Fat Mass and Obesity-associated protein) is a Fe(II)- and 2-oxoglutarate-dependent RNA demethylase that removes N6-methyladenosine (m6A) marks from nuclear transcripts, linking RNA epigenetics to energy balance, adipogenesis, and an expanding body of cancer biology. The unconjugated rabbit polyclonal reagent from Antibodies.com detects the endogenous human protein in western blot and immunohistochemistry workflows, making it a practical choice for laboratories studying m6A dynamics in cell lines and primary tissues.

Supplied as 100 µl of polyclonal serum, this reagent is intended for research use only and pairs with standard anti-rabbit HRP or fluorescent secondaries, depending on whether chromogenic or immunofluorescence detection is preferred. With reactivity directed against the human ortholog, the antibody supports studies in metabolic disease, leukemia, glioblastoma, and other contexts where FTO expression or localization is being compared across conditions. Typical sample inputs include whole-cell lysates for western blot and formalin-fixed paraffin-embedded sections for immunohistochemistry.