Anti-FSCN1 Antibody

The FSCN1 protein (Fascin Actin-Bundling Protein 1) is a 55 kDa actin-bundling protein critical for organizing F-actin into tight, parallel bundles within filopodia, lamellipodia, and invadopodia. This unconjugated rabbit polyclonal antibody from Antibodies.com targets FSCN1 for Western blot and immunohistochemistry workflows, with validated reactivity across human, mouse, and rat samples. Supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, the reagent ships as a 100 µl vial suitable for repeated experimental use. It is commonly deployed in studies of epithelial-mesenchymal transition, tumor cell invasion, and metastatic mechanisms, where elevated FSCN1 expression correlates with poor prognosis in carcinomas of the breast, colon, lung, and esophagus. The polyclonal format offers multi-epitope recognition, supporting detection of native and denatured FSCN1 in tissue sections and lysate preparations. Researchers investigating cytoskeletal remodeling, dendritic cell marker profiling in lymphoid tissue, or cancer cell motility rely on this reagent for reproducible band visualization in WB and clean cytoplasmic staining in IHC.